Development of a high-throughput device for liquid-phase microextraction coupled with gas chromatography-mass spectrometry for the determination of benzene derivatives in environmental water
A device coupled with an automatic gas chromatography injection sampler for high-throughput liquid-liquid microextraction has been proposed in this study. This study's main objective was to devise a trap vial directly placed in an automatic liquid sampler (ALS) to collect and inject the extract...
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Veröffentlicht in: | Analytical methods 2021-07, Vol.13 (25), p.2865-287 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | A device coupled with an automatic gas chromatography injection sampler for high-throughput liquid-liquid microextraction has been proposed in this study. This study's main objective was to devise a trap vial directly placed in an automatic liquid sampler (ALS) to collect and inject the extractant without a transfer step. Sixteen groups of microextraction procedures were performed simultaneously to increase the overall efficiency. The experimental parameters of the extraction method were optimized using a central composite design. Under the optimal conditions, the benzene derivatives' calibration curve was linear in the range of 0.1-200 μg L
−1
. The limit of detection (LOD) ranged from 0.016 to 0.16 μg L
−1
, and the limit of quantitation (LOQ) ranged from 0.046 to 0.50 μg L
−1
. The enrichment factors (EFs) ranged from 254 to 1094. Intraday and interday precision were found to be in the range of 2.2-6.2% (
n
= 3) and 4.0-6.3% (
n
= 9), respectively. The relative recovery of the four aqueous samples ranged from 69% to 121%. These experimental results indicated that the proposed device is reliable. Furthermore, it is simple, convenient and high-throughput.
A liquid phase microextraction device that does not require centrifugation and transfer of solvent. |
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ISSN: | 1759-9660 1759-9679 |
DOI: | 10.1039/d1ay00038a |