Green Synthesis of Zinc Oxide Nanoparticles (ZnO NPs) Using Cissus quadrangularis: Characterization, Antimicrobial and Anticancer Studies

In the present study, zinc oxide nanoparticles (ZnO NPs) were synthesized using the stem aqueous extracts of Cissus quadrangularis ( Cq ) and characterized using UV, FTIR, XRD, TEM, SAED and EDAX. The synthesized Cq -ZnO NPs showed its optical absorbance at 378 nm and observed as spherical particles with a size of about ~ 75 to 90 nm. The potential antibacterial activity of Cq -ZnO NPs showed an effective inhibition of M. smegmatis at 50 µg/ml when compared to other bacterial species. The antiproliferative effect was observed at 100 μg/ml on MIA PaCa-2 cell lines with IC 50 value of 7.02 ± 0.02 µg/ml at 24 h. The synthesized Cq -ZnO NPs was found potential activity against bacterial pathogens and cancer cells. Therefore, they may possibly be employed as useful antibacterial and antiproliferative agents.