Recent Advances in Organocatalytic Asymmetric Cycloaddition Reactions Through Ortho‐Quinone Methide Scaffolds

This review summarizes the very recent advances in organocatalytic asymmetric cycloaddition reactions involving ortho‐quinone methides (o‐QMs), a family of versatile species that have proven useful in a broad range of reactions to afford diverse chiral molecules. In the past years, different kinds of organocatalysts have been developed into a privileged class of catalytic systems in asymmetric synthesis. A number of remarkable achievements have been made by many groups around the world. Due to length limitation, this review only summarizes those works published from January 2016 to December 2020. Meanwhile, catalytic systems which combine metal catalysts and organocatalysts will not be discussed in this review. Ortho‐quinone methides (o‐QMs) are an important class of versatile species that have proven useful in synthetic organic chemistry, medicinal chemistry as well as materials chemistry. This Minireview summarized recent achievements in the exploration of o‐QMs in organocatalytic asymmetric cycloaddition reactions according to the type of catalytic systems published since 2016.