A comparative study on the effect of Warfarin v/s Acenocoumarol in patients with atrial fibrillation

[...]by rectifying these drawbacks we had conducted this study for a comparatively longer duration on a larger sample size. Inclusion criteria: * All adult patients with age >18 years with confirmed diagnosis of atrial fibrillation. * Patients who were on warfarin and acenocoumarol as anticoagulant therapy. * Patient who were willing to provide information through phone. Statistically significant betterment of QOL was seen in patients with use of acenocoumarol compared to warfarin over a number of domains which are physical functioning (acenocoumarol: 52.98±26.07; warfarin 40.60±30.76, p value 0.002), general health (acenocoumarol 74.31±20.25; warfarin 62.84±31.29, p value 0.002) and mental health (acenocoumarol 79.35±14.16, warfarin 73.67±13.36, p value 0.003). Warfarin group showed statistically significant association between medication adherence and TTR as well as medication adherence and quality of life domains like, physical functioning (40.60%), role physical (13.79%), general health (62.84%) and vitality (67.77%).