Ginkgolide B derivative synthesis and their effects on the viability of SKOV3 cells

The natural product Ginkgolide B was used as a raw material and modified by esterification on C10-OH or C1-OH to obtain 11 derivatives ( 1 – 11 ), which were structurally characterized with nuclear magnetic resonance spectroscopy. An MTT assay-based in vitro tumor proliferation inhibitory activity t...

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Veröffentlicht in:	Medicinal chemistry research 2021-06, Vol.30 (6), p.1265-1272
Hauptverfasser:	Feng, ZiLi, Zhu, ZhiBin, Chen, Wang, Xu, JiaYuan, Bai, Yu, Hu, DaiHua, Zhao, ZhengDong
Format:	Artikel
Sprache:	eng
Schlagworte:	Annexin V Apoptosis Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Esterification Ginkgolides Inorganic Chemistry Magnetic resonance spectroscopy Medicinal Chemistry Natural products NMR NMR spectroscopy Nuclear magnetic resonance Original Research Ovarian cancer Pharmacology/Toxicology
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