Influence of educational level on test and treatment for incident hypothyroidism

Objective The incidence of hypothyroidism is not expected to differ by socioeconomic factors. However, the decision to test and initiate treatment may differ. We aimed to examine whether educational level influences the probability of thyroid stimulation hormone (TSH)‐measurement and initiation of l...

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Veröffentlicht in:Clinical endocrinology (Oxford) 2021-06, Vol.94 (6), p.1025-1034
Hauptverfasser: Møllehave, Line Tang, Jacobsen, Rikke Kart, Linneberg, Allan, Skaaby, Tea, Knudsen, Nils, Jørgensen, Torben, Kårhus, Line Lund, Kriegbaum, Margit, Grand, Mia Klinten, Siersma, Volkert, Lind, Bent, Andersen, Christen Lykkegaard, Nygaard, Birte, Medici, Bjarke Borregaard, Pedersen, Inge Bülow, Ravn‐Haren, Gitte, Thuesen, Betina Heinsbæk
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Sprache:eng
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Zusammenfassung:Objective The incidence of hypothyroidism is not expected to differ by socioeconomic factors. However, the decision to test and initiate treatment may differ. We aimed to examine whether educational level influences the probability of thyroid stimulation hormone (TSH)‐measurement and initiation of levothyroxine treatment. Design Citizens in the greater Copenhagen Area during 2001‐2015 were included. Individual‐level data on educational level, diagnoses, GP‐contact, TSH‐measurement and medication were derived from administrative and healthcare registers. The relative risks (RR) between educational levels of annual TSH‐measurement and treatment initiation following a TSH‐measurement were analysed in Poisson regression models with generalized estimation equations. Results A TSH‐measurement was performed in 19% of 9,390,052 person years. The probability of TSH‐measurement was higher with short (RR 1.16 [95% CI 1.15–1.16]) and medium (RR 1.11 [95% CI 1.06–1.12]) compared with long education. Treatment was initiated after 0.8% of 2,049,888 TSH‐measurements. For TSH  10 mIU/L, RR was 1.07 (95% CI 1.02–1.12) for short and 1.08 (95% CI 1.03–1.13) for medium compared with long education. Conclusion The probability of TSH‐measurement was higher with shorter education, and the probability of treatment initiation with TSH > 10 mIU/L was marginally higher with short‐medium education compared with long education. However, the probability of treatment initiation with TSH 
ISSN:0300-0664
1365-2265
DOI:10.1111/cen.14429