Aviremic organ transplant dengue virus transmission – A case report
Dengue virus (DENV), a mosquito‐borne pathogen, causes systemic infections. There are no clear guidelines regarding the screening of donor blood is used in endemic countries to prevent blood transfusion or transplant‐associated dengue. DENV has been shown to be detected in urine samples even when DE...
Gespeichert in:
Veröffentlicht in: | American journal of transplantation 2021-05, Vol.21 (5), p.1944-1947 |
---|---|
Hauptverfasser: | , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | Dengue virus (DENV), a mosquito‐borne pathogen, causes systemic infections. There are no clear guidelines regarding the screening of donor blood is used in endemic countries to prevent blood transfusion or transplant‐associated dengue. DENV has been shown to be detected in urine samples even when DENV viremia is undetectable. We describe an incident of transplant‐associated dengue where the donor tested negative for DENV viremia but positive for DENV viuria resulting in the transmission of DENV to our two kidney recipients. Both recipients resolved DENV infection uneventfully, with no adverse impact on the renal graft. Our findings raise the consideration for revised screening recommendations in endemic countries to include DENV RT‐PCR in the urine.
The authors report on transplant‐associated dengue infection via aviremic renal transplantation. |
---|---|
ISSN: | 1600-6135 1600-6143 |
DOI: | 10.1111/ajt.16540 |