Cellular ATP Synthase

This review presents a collection and analysis of the currently available data on the structure and organization, localization, working mechanisms, and functions of the enzyme that synthesizes adenosine triphosphate (ATP), ATP synthase. It is universal (present in all prokaryotic and eukaryotic cells) in nature and is unique in its characteristics. The proper assembly and functioning of ATP synthase are the required conditions for the normal process of oxidative phosphorylation, the result of which is energy storage in the form of ATP. A large number of diseases, including neurodegenerative and mitochondrial diseases, are associated with ATP synthase disorders.