Molecular docking simulation of interaction between insulin and silica nanoparticle

Molecular docking simulation has been done in this research by using Hex version 8.0 software package, respectively, to explore the interaction between insulin and silica nanoparticle. Silica nanoparticle acts as receptor and insulin acts as ligand in this research. It was found that insulin form more stable interaction when it is in the pore of silica nanochannel than on the surface of silica nanosheet. Insulin prefer to interact with silica atoms than oxygen atoms in the pore of silica nanochannel