Chemistry and synthesis of Bis Pyrazole derivatives and their biological activity: a review

Pyrazole derivatives were used for all kinds of biological celerity like used for a core structure in a large of compounds that possess important pharmacological agents such as a potent anti-inflammatory, anti-obesity drug rimonabant, antitumor and analgesic. Various bis-pyrazole derivatives were introduced a great contribution not only in the synthetic chemistry but also used in the healthful chemistry field. In this review, we reported the different methods have been used for synthesis of pyrazole derivatives with some of them being used in the biological field.