A New Chlorinated Tetralone from Co-Culture of Insect-Pathogenic Beauveria bassiana and Phytopathogenic Nigrospora oryzae
In this study, the co-culture of Nigrospora oryzae and Beauveria bassiana , the pathogenic endophytes in the seeds of Dendrobium officinale , were examined for their antagonistic relationship by the production of metabolite. One new chlorotetralone ( 1 ) and five known compounds, murranoic acid A (...
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| Veröffentlicht in: | Chemistry of natural compounds 2021-03, Vol.57 (2), p.297-299 |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | In this study, the co-culture of
Nigrospora oryzae
and
Beauveria bassiana
, the pathogenic endophytes in the seeds of
Dendrobium officinale
, were examined for their antagonistic relationship by the production of metabolite. One new chlorotetralone (
1
) and five known compounds, murranoic acid A (
2
), 9,12,13-trihydroxy-10-octadecenoic acid (
3
), 3,3′-methylenebis(4-hydroxy-6-methyl-2
H
-pyran-2-one) (
4
), sclerin (
5
), and (4S)-4,6,8-trihydroxy-3,4-dihydro-1(2
H
)-naphthalen-1-one (
6
), were isolated. Compounds
1
–
5
showed antifungal activity against
B. bassiana
with MICs of 256, 128, 2, 32, and 64 μg/mL, and
N. oryzae
with MICs of 64, 256, 256, 256, and 64 μg/mL. Compound
4
showed significant antifungal activity against co-culture of
B. bassiana
and
N. oryzae
with MIC at 1 μg/mL. |
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| ISSN: | 0009-3130 1573-8388 |
| DOI: | 10.1007/s10600-021-03343-9 |