Multifunctional applications of Nickel oxide (NiO) nanoparticles synthesized by facile green combustion method using Limonia acidissima natural fruit juice

[Display omitted] •Simple Green Chemistry route were employed to synthesize NiO NPs with Limonia acidissima fruit juice.•NiO NPs shows good photocatalytic activity for the degradation of carcinogenic dye such as methylene blue.•Antioxidant bioactivity of the NiO NPs has an ability to scavenge reactive O and N species.•NiO NPs could inhibit tumor cell invasion and metastasis by angiogenesis studies.•Electrochemical sensing property to detect trace amount of DA with the LOD of 11 µM. In this work, NiO nanoparticles (NPs) have been effectively synthesized by a simple, efficient and cost effective method using limonia accidissima natural fruit juice as a novel fuel. The synthesized NPs were characterized by XRD, FT-IR, UV-DRS, SEM-EDAX, TEM and PL studies. X-ray diffraction pattern confirms the cubic structured NiO with average crystallite size of 13, 21, 20, 12 and 10 nm. The band at 430 cm−1 in FT-IR indicates the stretching mode of the Ni-O bond. The band gap of the material was found to be 3.4 eV. SEM and TEM analysis reveals that the morphologies are spherical in shape and having the particle size about 20–25 nm. Surface defects were studied by photoluminescence (PL) spectroscopy. Photocatalytic activities of the synthesised NPs were used to degrade methylene blue dye. The in-depth antioxidant activity of synthesized NPs were analysed by DPPH, ferrous ion and hydroxyl radical methods. Anti angiogenic activity was examined by CAM assay. Finally, NiO NPs were used for the electrochemical sensing of dopamine (DA), which is able to sense up to the detection limit of 11 μM.