Flash Chemistry Makes Impossible Organolithium Chemistry Possible

Flash Chemistry Makes Impossible Organolithium Chemistry Possible

Organolithium reagents are often too unstable to use due to being highly reactive. This limits their application in organic synthesis. This review highlights our approach to various synthetic reactions mediated by organolithium reagents based on flash chemistry conducted in flow reactors, especially...

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Veröffentlicht in:Chemistry letters 2021-03, Vol.50 (3), p.485-492
Hauptverfasser: Nagaki, Aiichiro, Ashikari, Yosuke, Takumi, Masahiro, Tamaki, Takashi
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Reactors
Reagents
Vol. 50 Commemorative Highlight Review: Molecular Chemistry
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container_end_page 492
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container_title Chemistry letters
container_volume 50
creator Nagaki, Aiichiro
Ashikari, Yosuke
Takumi, Masahiro
Tamaki, Takashi
description Organolithium reagents are often too unstable to use due to being highly reactive. This limits their application in organic synthesis. This review highlights our approach to various synthetic reactions mediated by organolithium reagents based on flash chemistry conducted in flow reactors, especially utilizing space-integration of the flow reactions.
doi_str_mv 10.1246/cl.200837
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source Oxford University Press Journals All Titles (1996-Current)
subjects Reactors
Reagents
Vol. 50 Commemorative Highlight Review: Molecular Chemistry
title Flash Chemistry Makes Impossible Organolithium Chemistry Possible
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