Viral Biophysics: Contributions to Drug Modalities

Viral Biophysics: Contributions to Drug Modalities

Recent virological researches using biophysical methods, termed as virus biophysics or virophysics, largely contribute to the development of anti-viral drugs and vaccines. In this review, examples of structural and physicochemical analyses for representative viruses to develop drug modalities such a...

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Veröffentlicht in:Seibutsu Butsuri 2021, Vol.61(2), pp.082-089
Hauptverfasser: MAENAKA, Katsumi, FUKUHARA, Hideo, HASHIGUCHI, Takao, CAAVEIRO, Jose M. M., NAGATOISHI, Satoshi, KURODA, Daisuke, TSUMOTO, Kouhei
Format: Artikel
Sprache:eng ; jpn
Schlagworte:
Antibodies
Antiviral agents
Biophysics
broadly neutralizing antibodies
cryo-electron microscopy
Drug development
drug modality
interaction analysis
Vaccines
virus
Viruses
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Beschreibung
Zusammenfassung:Recent virological researches using biophysical methods, termed as virus biophysics or virophysics, largely contribute to the development of anti-viral drugs and vaccines. In this review, examples of structural and physicochemical analyses for representative viruses to develop drug modalities such as small compounds, antibodies, and vaccines are explained, and future direction of biophysical research for virus research is also discussed.
ISSN:0582-4052
1347-4219
DOI:10.2142/biophys.61.082