Synthesis of 4,4′-substituted 2,2′-[ethane-1,2-diylbis(selanediyl)]bis(1H-imidazol-5(4H)-ones)

Synthesis of new bis(seleno-imidazolone) derivatives bearing the alkyl and aryl moieties at the N(1) atom of the five-membered ring was developed. Cytotoxicity of the synthesized compounds against A549, VA-13, MCF-7, and HEK293T cell lines was evaluated.

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Veröffentlicht in:Russian chemical bulletin 2021-03, Vol.70 (3), p.457-462
Hauptverfasser: Finko, A. V., Sokolov, A. I., Vasilyeva, L. A., Skvortsov, D. A., Al-Khazraji, A. S. H., Ofitserov, E. N., Zyk, N. V., Majouga, A. G., Beloglazkina, E. K.
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Sprache:eng
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Zusammenfassung:Synthesis of new bis(seleno-imidazolone) derivatives bearing the alkyl and aryl moieties at the N(1) atom of the five-membered ring was developed. Cytotoxicity of the synthesized compounds against A549, VA-13, MCF-7, and HEK293T cell lines was evaluated.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-021-3108-4