Annona muricata leaves ethanolic extract in water, n-hexane, and methanol fractions: Cytotoxicity assay, antioxidant activity, flavonoid content, polyphenol content, and acetogenin content
Cytotoxicity, antioxidant activity, and a total bioactive assay of the ethanolic extract of Annona muricata leave partitioned into water, n-hexane, and methanol fractions were investigated. The brine shrimp lethality test used for the cytotoxicity assay gave the LC50 values of 84 and 1 ppm for the n...
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| creator | Krisanti, Elsa Anisa Harumanti, Afidya Indina Mulia, Kamarza |
| description | Cytotoxicity, antioxidant activity, and a total bioactive assay of the ethanolic extract of Annona muricata leave partitioned into water, n-hexane, and methanol fractions were investigated. The brine shrimp lethality test used for the cytotoxicity assay gave the LC50 values of 84 and 1 ppm for the n-hexane and methanol fractions, respectively. The antioxidant activity determined using DPPH reagent gave IC50 values of 40, 15, and 8 ppm for the n-hexane, water, and methanol fractions, respectively. In addition, the total polyphenol and the total acetogenin content of the methanol fraction were also the highest among the three fractions. These results indicate that the methanol fraction of the Annona muricata has the highest potential as a source for naturally occurring antitumor and antioxidant compounds. |
| doi_str_mv | 10.1063/5.0047484 |
| format | Conference Proceeding |
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These results indicate that the methanol fraction of the Annona muricata has the highest potential as a source for naturally occurring antitumor and antioxidant compounds.</description><subject>Antioxidants</subject><subject>Assaying</subject><subject>Biocompatibility</subject><subject>Cytotoxicity</subject><subject>Hexanes</subject><subject>Lethality</subject><subject>Methanol</subject><subject>Reagents</subject><subject>Toxicity testing</subject><issn>0094-243X</issn><issn>1551-7616</issn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2021</creationdate><recordtype>conference_proceeding</recordtype><recordid>eNp9kc1OwzAMxyMEEmNw4A0icUPrSNqkWbmhiS9pEheQuFVemrBMXVKarKzvxsORahPcOFm2f_bfHwhdUjKlJM9u-JQQJtiMHaER5ZwmIqf5MRoRUrAkZdn7KTrzfk1IWggxG6HvO2udBbzZtkZCAFwr6JTHKqzAutpIrHahBRmwsfgLgmon2CYrtQOrJhhshTcHFOsBM876WzzvgwtuZ6QJPQbvoR_YmNyZKlo8gF3MTbCuoXPWmQpLZ4OyYYIbV_fNSg0tf2ODEEgV3IeycZBD_BydaKi9ujjYMXp7uH-dPyWLl8fn-d0ikWmRhQQ0EUxzQVjKaEV0KkmR50xKSmcaCrZUlaS5ZstKLQsQWZ5xLlMei0QhdXTH6Grft2nd51b5UK7dtrVRsowYI4ILQSN1vad8XBuGS5RNazbQ9mXn2pKXh8-UTaX_gykph1f-FWQ_e6mVFA</recordid><startdate>20210323</startdate><enddate>20210323</enddate><creator>Krisanti, Elsa Anisa</creator><creator>Harumanti, Afidya Indina</creator><creator>Mulia, Kamarza</creator><general>American Institute of Physics</general><scope>8FD</scope><scope>H8D</scope><scope>L7M</scope></search><sort><creationdate>20210323</creationdate><title>Annona muricata leaves ethanolic extract in water, n-hexane, and methanol fractions: Cytotoxicity assay, antioxidant activity, flavonoid content, polyphenol content, and acetogenin content</title><author>Krisanti, Elsa Anisa ; Harumanti, Afidya Indina ; Mulia, Kamarza</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c293t-af074f5704241d0f2c09664cc118fa94bedc16f4bdeb9a736355c2507479cf363</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Antioxidants</topic><topic>Assaying</topic><topic>Biocompatibility</topic><topic>Cytotoxicity</topic><topic>Hexanes</topic><topic>Lethality</topic><topic>Methanol</topic><topic>Reagents</topic><topic>Toxicity testing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Krisanti, Elsa Anisa</creatorcontrib><creatorcontrib>Harumanti, Afidya Indina</creatorcontrib><creatorcontrib>Mulia, Kamarza</creatorcontrib><collection>Technology Research Database</collection><collection>Aerospace Database</collection><collection>Advanced Technologies Database with Aerospace</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Krisanti, Elsa Anisa</au><au>Harumanti, Afidya Indina</au><au>Mulia, Kamarza</au><au>Rahman, Siti Fauziyah</au><au>Whulanza, Yudan</au><au>Lischer, Kenny</au><au>Supriadi, Sugeng</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Annona muricata leaves ethanolic extract in water, n-hexane, and methanol fractions: Cytotoxicity assay, antioxidant activity, flavonoid content, polyphenol content, and acetogenin content</atitle><btitle>AIP conference proceedings</btitle><date>2021-03-23</date><risdate>2021</risdate><volume>2344</volume><issue>1</issue><issn>0094-243X</issn><eissn>1551-7616</eissn><coden>APCPCS</coden><abstract>Cytotoxicity, antioxidant activity, and a total bioactive assay of the ethanolic extract of Annona muricata leave partitioned into water, n-hexane, and methanol fractions were investigated. 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| identifier | ISSN: 0094-243X |
| ispartof | AIP conference proceedings, 2021, Vol.2344 (1) |
| issn | 0094-243X 1551-7616 |
| language | eng |
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| source | AIP Journals Complete |
| subjects | Antioxidants Assaying Biocompatibility Cytotoxicity Hexanes Lethality Methanol Reagents Toxicity testing |
| title | Annona muricata leaves ethanolic extract in water, n-hexane, and methanol fractions: Cytotoxicity assay, antioxidant activity, flavonoid content, polyphenol content, and acetogenin content |
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