Cataract Formation by Near‐infrared Radiation in Rabbits

Surveys and epidemiological studies have shown an increased prevalence of cataracts in workers in the glass and steel industries. These cataracts are associated with exposure to intense infrared radiation (IR) emitted from heated materials and industrial furnaces. Thermal model calculations predicted that near and far IR would cause cataract with different mechanisms. The present study investigated cataract formation by near IR. Eyes of pigmented rabbits were exposed to IR at a wavelength of 808 nm. Morphological changes in the anterior segment of the eye were assessed by slit‐lamp microscopy, and temperature distributions in the anterior chamber of the eye were observed during IR exposure using microencapsulated thermochromic liquid crystals. Cortical cataract appeared below the exposed area of the iris in eyes that had been exposed for 6 min to an irradiance of 1.27 W cm−2 or higher. The monitored temperature in the anterior chamber began to increase in the region adjacent to the exposed area of the iris with the onset of IR exposure. These results demonstrate that 808‐nm IR is absorbed and converted to heat within the iris, which is then conducted to the lens and produce a cataract, as Goldmann theory states. Eyes of pigmented rabbits were exposed to infrared radiation (IR) at a wavelength of 808 nm to investigate cataract formation by near IR. Temperature in the anterior chamber began to increase in the region adjacent to the exposed area of the iris with the onset of IR exposure. One day after IR exposure, cortical cataract appeared below the exposed area of the iris. These results demonstrate that 808‐nm IR is absorbed and converted to heat within the iris, which is then conducted to the lens and produce a cataract.