Optical coherence tomography indices in the diagnosis and discrimination of stages of primary open-angle glaucoma in an African population

Purpose The objective of this study was to determine the structure–function association of the optical coherence tomography (OCT) indices (retinal nerve fibre layer (RNFL), ganglion cell complex (GCC) and optic nerve head (ONH) parameters) with the visual field sensitivity and their diagnostic ability at different stages of primary open-angle glaucoma (POAG) among a population West-African descent. Methods The study was a clinic-based prospective study which employed purposive sampling in the recruitment of clinically diagnosed POAG and non-glaucoma patients. OCT and visual field test (VFT) results were collated. Classification of the POAG cases was done using the Hodapp–Parrish–Anderson criteria. ROC was used for assessing the diagnostic ability of OCT indices. Pearson’s correlation was used to assess the structure–function association. P value