Hyperbaric oxygen therapy for bleeding due to gastritis induced by chemoradiotherapy for regional recurrence of esophageal cancer post-radical esophagectomy

Chemoradiotherapy is effective for locoregional recurrence of esophageal cancer after esophagectomy, although it is important to watch out for adverse events, especially following the late phase. We encountered a patient with bleeding from the gastric conduit caused by chemoradiation-induced gastritis after chemoradiotherapy for mediastinal lymph node recurrence post-radical esophagectomy for esophageal cancer. A 58-year-old male was undergoing chemoradiotherapy for mediastinal lymph node recurrence. About 3 months after the start of the therapy, the patient presented with anemia and bleeding from the gastric conduit caused by chemoradiation-induced gastritis as assessed by fiber optic upper gastrointestinal endoscopy and blood examination. Multiple sessions of argon plasma coagulation for ablation of the gastric mucosal telangiectasia proved ineffective. However, hyperbaric oxygen therapy was effective and the symptom has not recurred until date after this therapy.