Synthesis and characterization of anti-adhesion tricomposite electrospun nanofiber barrier membrane for use in post-surgical adhesion conditions

[Display omitted] •Novel anti-adhesion tricomposite electrospun nanofibers membrane synthesized as barrier membrane.•The barrier membranes showed superior properties suitable for use as anti-adhesion barrier membranes.•It can be used as an alternative to address the drawbacks of currently available barrier membranes. Adhesion formation is a crucial post-surgical problem that needs to be addressed by clinicians. In this study, we report the synthesis of a novel tricomposite electrospun nanofiber membrane as a potential barrier for the prevention of post-surgical adhesion. The synthesized membrane was characterized using suitable techniques. The membrane showed excellent hydrophilicity (15.2° contact angle), mechanical stability (5.04 MPa with a strain of 50%) and biocompatibility (cell viability of 106%) required for a potential barriers membrane to be used in post adhesion surgical condition. This membrane can be an alternative membrane to address the drawbacks of currently used antiadhesion barrier membrane.