Eosinophilic gastroenteritis and graft‐versus‐host disease induced by transmission of Norovirus with fecal microbiota transplant

Fecal microbiota transplantation (FMT) was performed to decolonize gastrointestinal tract from antibiotic‐resistant bacteria before allogeneic hematopoietic cells transplantation (alloHCT). AlloHCT was complicated by norovirus gastroenteritis, acute graft‐versus‐host disease, and eosinophilic pancol...

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Veröffentlicht in:Transplant infectious disease 2021-02, Vol.23 (1), p.e13386-n/a
Hauptverfasser: Bilinski, Jaroslaw, Lis, Karol, Tomaszewska, Agnieszka, Pechcinska, Aleksandra, Grzesiowski, Pawel, Dzieciatkowski, Tomasz, Walesiak, Alicja, Gierej, Beata, Ziarkiewicz‐Wróblewska, Bogna, Tyszka, Martyna, Kacprzyk, Piotr, Chmielewska, Lidia, Waszczuk‐Gajda, Anna, Wiktor‐Jedrzejczak, Wieslaw, Basak, Grzegorz W.
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Sprache:eng
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Zusammenfassung:Fecal microbiota transplantation (FMT) was performed to decolonize gastrointestinal tract from antibiotic‐resistant bacteria before allogeneic hematopoietic cells transplantation (alloHCT). AlloHCT was complicated by norovirus gastroenteritis, acute graft‐versus‐host disease, and eosinophilic pancolitis. Norovirus was identified in samples from FMT material. Symptoms resolved after steroids course and second norovirus‐free FMT from another donor.
ISSN:1398-2273
1399-3062
DOI:10.1111/tid.13386