Pulmonary Vascular Resistance in Pulmonary Arterial Hypertension: La Pièce de Résistance?/ Reply to Weatherald et al.: Pulmonary Vascular Resistance in Pulmonary Arterial Hypertension: La Pièce de Résistance?

Badagliacca et al respond to Weatherald and colleagues regarding their article about pulmonary vascular resistance in pulmonary arterial hypertension. They acknowledge Weatherald and colleagues for their supportive comments, and pleasant reminiscence of French cuisine, on their recent report on risk reduction and hemodynamics after initial dual combination of therapies in pulmonary arterial hypertension. They fully agree on the importance of pulmonary vascular resistance combined with imaging of the right heart, as there may be dissociation, although this is unlikely when pulmonary vascular resistance decreases by more than 50-60%.