Double-exposure method for speckle-tracking x-ray phase-contrast microtomography

X-ray phase-contrast microtomography based on speckle tracking is an attractive method for non-destructive three-dimensional imaging owing to its simple setup and ability to yield absorption, refractive, and scattering images simultaneously. However, the edge-enhancement effect usually results in im...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of applied physics 2021-02, Vol.129 (7)
Hauptverfasser: Yu, Fucheng, Li, Ke, Wang, Feixiang, Zhang, Haipeng, Ju, Xiaolu, Xu, Mingwei, Du, Guohao, Deng, Biao, Xie, Honglan, Xiao, Tiqiao
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:X-ray phase-contrast microtomography based on speckle tracking is an attractive method for non-destructive three-dimensional imaging owing to its simple setup and ability to yield absorption, refractive, and scattering images simultaneously. However, the edge-enhancement effect usually results in image artifacts or inaccurate phase retrieval, limiting the extensive application of this method in biomedical research and for low-Z materials. In this paper, a double-exposure method is introduced to solve this problem efficiently and accurately. Pure phase samples with various microstructures and densities and a biological sample with a distinct edge-enhancement effect were used to verify the effectiveness of the developed method. In an experiment performed using a polymer phantom with an evenly distributed density, 17 irregularly shaped particles with diameters ranging from 15 to 25 μm were successfully reconstructed with the effective elimination of the edge-enhancement effect. The results obtained for a sample composed of different polymer materials demonstrated that, in contrast with the traditional speckle-tracking method, the present method is able to discriminate materials with similar x-ray attenuations. Finally, experiments were performed using a dehydrated fish, which entail typical edge enhancement and a complex microstructure; notably, it was verified that the fine structure of the fish, including its fins and intestines, was reconstructed completely using the proposed method, whereas the standard speckle-tracking method was ineffective. In conclusion, the developed double-exposure method can serve as an efficient and accurate technique for the x-ray phase-contrast microtomography of samples comprising low-Z materials and complicated microstructures.
ISSN:0021-8979
1089-7550
DOI:10.1063/5.0043053