Synthesis, Structure, and Biological Activity of Mixed-Ligand Amine-Containing Copper(II) Coordination Compounds with 2-(2-Hydroxybenzylidene)-N-(prop-2-en-1-yl)hydrazinecarbothioamide

Сopper(II) nitrate reacts in ethanol with 2-(2-hydroxybenzylidene)- N -(prop-2-en-1-yl)hydrazinecarbothioamide H 2 L in an 1 : 1 molar ratio to form the coordination compound Cu(HL)NO 3 ·H 2 O. The introduction of amines [imidazole (Im), 3,5-dibromopyridine (3,5-Br 2 Py), and 4-methylpyridine (4-Pic)] into the reaction mixture in a molar ratio 1 : 1 : 2 leads to the formation of CuA(HL)NO 3 · n H 2 O [A = Im, 3,5-Br 2 Py, 4-Pic; n = 0, 3] complexes. The structure of the obtained compounds was determined by X-ray structural analysis. The synthesized complexes exhibit antimicrobial, antifungal, antioxidant, and anticancer activities.