Improving the drug dissolution profile of poorly aqueous soluble lovastatin using hydrophilic polymers by solid dispersion and physical mixing techniques

[...]this approach of SD technique utilizing the above-mentioned carriers could be employed as a substantial formulation strategy to enhance the in vitro dissolution rate which, in turn, may improve the oral bioavailability of the water-insoluble drugs. [...]dissolution is considered as the rate det...

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Veröffentlicht in:	National journal of physiology, pharmacy and pharmacology pharmacy and pharmacology, 2021-01, Vol.11 (2), p.1-221
Hauptverfasser:	Sarkar, Md, M, Yasif, M, Monjur, Sharmin, Nahid
Format:	Artikel
Sprache:	eng
Schlagworte:	Dissolution Investigations Polyethylene glycol Scanning electron microscopy
Online-Zugang:	Volltext
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