Phenolic Constituents with their α-Glucosidase Inhibitory Activities from the Leaves of Viburnum melanocarpum

Phenolic Constituents with their α-Glucosidase Inhibitory Activities from the Leaves of Viburnum melanocarpum

A new compound 1 , together with two known compounds ( 2 , 3 ), has been isolated from the ethanolic extract of Viburnum melanocarpum leaves. Their structures were elucidated by extensive spectroscopic evidence and chemical method. In the in vitro assay, compounds 1 and 3 displayed potent inhibitory...

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Veröffentlicht in:Chemistry of natural compounds 2021, Vol.57 (1), p.56-58
Hauptverfasser: Tang, Yi-Yuan, Zhao, Zi-Yang, Chen, Jia, Zhao, Chun-Chao, Shao, Jian-Hua
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Glucosidase
In vitro methods and tests
Organic Chemistry
Plant Sciences
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Zusammenfassung:A new compound 1 , together with two known compounds ( 2 , 3 ), has been isolated from the ethanolic extract of Viburnum melanocarpum leaves. Their structures were elucidated by extensive spectroscopic evidence and chemical method. In the in vitro assay, compounds 1 and 3 displayed potent inhibitory activity against α-glucosidase with IC 50 values of 6.28 μM and 12.73 μM, respectively.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-021-03281-6