Multicomponent synthesis of nicotinic acid derivatives

Multicomponent synthesis of nicotinic acid derivatives

The synthesis of previously unknown nitriles, esters, and an amide of 6-alkoxy-2-alkylsulfanyl-4-methyl(4,4-dimethyl)nicotinic acid has been developed. The structure of a number of the obtained derivatives was proved by X-ray structural analysis.

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Bibliographische Detailangaben
Veröffentlicht in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2020-12, Vol.56 (12), p.1579-1585
Hauptverfasser: Dyachenko, Ivan V., Dyachenko, Vladimir D., Dorovatovskii, Pavel V., Khrustalev, Victor N., Nenajdenko, Valentine G.
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Chemistry and Materials Science
Derivatives
Esters
Niacin
Nicotinic acid
Nitriles
Organic Chemistry
Pharmacy
Structural analysis
Synthesis
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Zusammenfassung:The synthesis of previously unknown nitriles, esters, and an amide of 6-alkoxy-2-alkylsulfanyl-4-methyl(4,4-dimethyl)nicotinic acid has been developed. The structure of a number of the obtained derivatives was proved by X-ray structural analysis.
ISSN:0009-3122
1573-8353
DOI:10.1007/s10593-020-02852-9