Two-point Dixon fat-water swapping artifact: lesion mimicker at musculoskeletal T2-weighted MRI

Fat-water swapping is an artifact specific to chemical shift encoded MRI and so-called Dixon methods. It is more frequent using the 2-point than the multi-point (> 2) Dixon method. Actually, fat-water swapping on the 2-point Dixon sequences partly triggered the development of the multi-point techniques. Fat-water swapping occurs on post-processing calculated fat- and water-only images, but not on the directly acquired in-phase and out-of-phase source images. It originates from a natural ambiguity between fat and water peaks that may cause inverted calculation between fat- and water-only voxels. Fat-water swapping artifact over large areas encompassing multiple tissues can easily be recognized, but it may be confusing when the calculation errors are limited to a single anatomic structure or a small area, especially on T2-weighted images. We report four cases with 2-point Dixon fat-water swapping artifacts mimicking musculoskeletal lesions at T2-weighted MRI and propose hints to avoid misinterpretation.