Comparative analysis of the processes of collagen concentration by ultrafiltration using different types of membranes
Tangential flow filtration of the collagen protein solutions with a molecular weight 12, 14, and 24 kDa is investigated using flat sheet membranes. The effects of tangential ultrafiltration (UF) on the permeate properties using two regenerated celluloses (RCs) and two polyethersulfone (PES) membrane...
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Veröffentlicht in: | Journal of applied polymer science 2021-03, Vol.138 (12), p.n/a |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Tangential flow filtration of the collagen protein solutions with a molecular weight 12, 14, and 24 kDa is investigated using flat sheet membranes. The effects of tangential ultrafiltration (UF) on the permeate properties using two regenerated celluloses (RCs) and two polyethersulfone (PES) membranes with molecular weight cut‐off (MWCO) of 5 and 10 kDa are reported. The permeate and concentrate obtained in the UF experiments are characterized from a physical–chemical point of view by determining the temperature, pH, electrical conductivity, nitrogen content, and protein concentration. In addition, the experimental data are modeled using Hermia's model. The UF experiments demonstrated that permeate flux declined with increasing molecular weight of collagen at constant concentration (1%). Regardless of the molecular weight of collagen, the rejections decrease in the following order: PES 5 kDa > RC5kDa > RC10kDa > PES10kDa. In case of membrane with higher MWCO, the clogging phenomenon is mainly due to the blockage of the internal pores of the membrane than the formation of a polarization layer. Morphologies and characteristics of the membranes are characterized using scanning electron microscopy.
Fouling of ultrafiltration membranes due to the deposition of collagen macromolecules with different molecular weights on their surface and also in the membranes pores leads to the decrease in permeate fluxes with the increase in volume of the collagen permeate. |
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ISSN: | 0021-8995 1097-4628 |
DOI: | 10.1002/app.50055 |