Pancreatic neuroendocrine neoplasms - management guidelines (recommended by the Polish Network of Neuroendocrine Tumours)

We present revised diagnostic and therapeutic guidelines for the management of pancreatic neuroendocrine neoplasms (PNENs) proposed by the Polish Network of Neuroendocrine Tumours.These guidelines refer to biochemical (determination of specific and nonspecific neuroendocrine markers) and imaging dia...

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Veröffentlicht in:Endokrynologia Polska 2013, Vol.64 (6), p.459-479
Hauptverfasser: Kos-Kudła, Beata, Hubalewska-Dydejczyk, Alicja, Kuśnierz, Katarzyna, Lampe, Paweł, Marek, Bogdan, Nasierowska-Guttmejer, Anna, Nowakowska-Duława, Ewa, Pilch-Kowalczyk, Joanna, Sowa-Staszczak, Anna, Rosiek, Violetta
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container_end_page 479
container_issue 6
container_start_page 459
container_title Endokrynologia Polska
container_volume 64
creator Kos-Kudła, Beata
Hubalewska-Dydejczyk, Alicja
Kuśnierz, Katarzyna
Lampe, Paweł
Marek, Bogdan
Nasierowska-Guttmejer, Anna
Nowakowska-Duława, Ewa
Pilch-Kowalczyk, Joanna
Sowa-Staszczak, Anna
Rosiek, Violetta
description We present revised diagnostic and therapeutic guidelines for the management of pancreatic neuroendocrine neoplasms (PNENs) proposed by the Polish Network of Neuroendocrine Tumours.These guidelines refer to biochemical (determination of specific and nonspecific neuroendocrine markers) and imaging diagnostics (EUS, CT, MR, and radioisotope examination with a 68Ga or 99Tc labelled somatostatin analogue).A histopathological diagnostic, which determines the further management of patients with PNENs, must be necessarily confirmed by immunohistochemical tests. PNENs therapy requires collaboration between a multidisciplinary team of specialists experienced in the management of these neoplasms. Surgery is the basic form of treatment. Medical therapy requires a multidirectional procedure, and therefore the rules of biotherapy, peptide receptor radionuclide therapy, chemotherapy and molecular targeted therapy are discussed.
doi_str_mv 10.5603/EP.2013.0031
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subjects Clinical Competence
Endocrinology - standards
Humans
Medical Oncology - standards
Neuroendocrine tumors
Neuroendocrine Tumors - diagnosis
Neuroendocrine Tumors - therapy
Pancreatic cancer
Pancreatic Neoplasms - diagnosis
Pancreatic Neoplasms - therapy
Poland
Practice Guidelines as Topic
Quality Assurance, Health Care - standards
Radiation therapy
title Pancreatic neuroendocrine neoplasms - management guidelines (recommended by the Polish Network of Neuroendocrine Tumours)
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