How much testing and social distancing is required to control COVID-19? Some insight based on an age-differentiated compartmental model

In this paper, we provide insights on how much testing and social distancing is required to control COVID-19. To this end, we develop a compartmental model that accounts for key aspects of the disease: 1) incubation time, 2) age-dependent symptom severity, and 3) testing and hospitalization delays;...

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Veröffentlicht in:arXiv.org 2020-11
Hauptverfasser: Grundel, Sara, Heyder, Stefan, Hotz, Thomas, Ritschel, Tobias K S, Sauerteig, Philipp, Worthmann, Karl
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Sprache:eng
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Zusammenfassung:In this paper, we provide insights on how much testing and social distancing is required to control COVID-19. To this end, we develop a compartmental model that accounts for key aspects of the disease: 1) incubation time, 2) age-dependent symptom severity, and 3) testing and hospitalization delays; the model's parameters are chosen based on medical evidence, and, for concreteness, adapted to the German situation. Then, optimal mass-testing and age-dependent social-distancing policies are determined by solving optimal control problems both in open loop and within a model predictive control framework. We aim to minimize testing and/or social distancing until herd immunity sets in under a constraint on the number of available intensive care units. We find that an early and short lockdown is inevitable but can be slowly relaxed over the following months.
ISSN:2331-8422