Synthesis, structural elucidation and bioassay of morpholine/thiomorpholine and piperidine containing oxazoles

Synthesis, structural elucidation and bioassay of morpholine/thiomorpholine and piperidine containing oxazoles

The series of novel oxazole derivatives (3-4) have been synthesized. All the entitles compounds were characterized by IR, 1H, 13C NMR, mass spectra. All the lead compounds were tested for antimicrobial activity. The compound 4f having chloro substituent on the aromatic ring displays greater antimicr...

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Bibliographische Detailangaben
Hauptverfasser: Sravya, G., Reddy, N. Bakthavatchala, Zyryanov, Grigory V.
Format: Tagungsbericht
Sprache:eng
Schlagworte:
Antiinfectives and antibacterials
Antimicrobial agents
Aromatic compounds
Lead compounds
Mass spectra
Morpholine
NMR
Nuclear magnetic resonance
Oxazole
Piperidine
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Beschreibung
Zusammenfassung:The series of novel oxazole derivatives (3-4) have been synthesized. All the entitles compounds were characterized by IR, 1H, 13C NMR, mass spectra. All the lead compounds were tested for antimicrobial activity. The compound 4f having chloro substituent on the aromatic ring displays greater antimicrobial activity particularly against P. aeruginosa and P. crysogenum.
ISSN:0094-243X
1551-7616
DOI:10.1063/5.0018089