Antioxidant activity of new azanorbornene copolymers

Antioxidant activity of new azanorbornene copolymers

The copolymers of N-methyl-2-azanorbornene-5 (MAN), N-benzyl-2-azanorbornene-5 (BAN), N-allyl-2- azanorbornene-5 (AAN) and N-(2-azanorbornene-5)methylacetate (MAAN) with N-vinylpyrrolidone (VP) have been obtained by free radical polymerization. New copolymers were evaluated for their antioxidant pro...

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Bibliographische Detailangaben
Hauptverfasser: Gorbunova, E. A., Gorbunova, M. N.
Format: Tagungsbericht
Sprache:eng
Schlagworte:
Antioxidants
Copolymers
Erythrocytes
Free radical polymerization
Free radicals
Hydrogen peroxide
Lipid peroxidation
Lipids
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Zusammenfassung:The copolymers of N-methyl-2-azanorbornene-5 (MAN), N-benzyl-2-azanorbornene-5 (BAN), N-allyl-2- azanorbornene-5 (AAN) and N-(2-azanorbornene-5)methylacetate (MAAN) with N-vinylpyrrolidone (VP) have been obtained by free radical polymerization. New copolymers were evaluated for their antioxidant properties in lipid peroxidation induced by iron/ascorbate and in erythrocyte hemolysis by H2O2. The copolymer of BAN-VP has found to inhibit lipid peroxidation in liver homogenate.
ISSN:0094-243X
1551-7616
DOI:10.1063/5.0018395