The associations between phosphatidylethanolamine N-methyltransferase gene, dietary choline intake and anxiety and depression in healthy UK adults

In England, one in six adults met the criteria for a common mental disorder (CMD) such as anxiety or depression in 2014. [...]women were more likely to experience CMD symptoms than men(1). Choline intake was quantified using the United States Department of Agriculture food composition database consi...

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Veröffentlicht in:Proceedings of the Nutrition Society 2020, Vol.79 (OCE3), Article E784
Hauptverfasser: Harrison, K., Foster-Brown, C., Kelaiditis, C., Mavrommatis, Y., Pilic, L.
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container_issue OCE3
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Foster-Brown, C.
Kelaiditis, C.
Mavrommatis, Y.
Pilic, L.
description In England, one in six adults met the criteria for a common mental disorder (CMD) such as anxiety or depression in 2014. [...]women were more likely to experience CMD symptoms than men(1). Choline intake was quantified using the United States Department of Agriculture food composition database considering it is not a part of the UK food composition tables. Within the abnormal anxiety group, the mean anxiety scores were higher in carriers of the rs4646343 risk allele compared to those homozygous for the G allele (GT+TT 13.8 ± 2.3 vs GG 11.5 ± 1.2, p = 0.018, Mann-Whitney U test).
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source Cambridge Journals
subjects Adults
Alleles
Anxiety
Choline
Composition
Dietary intake
Food
Food composition
Government agencies
Health care
Men
Mental depression
Mental disorders
Methyltransferase
N-Methyltransferase
Phosphatidylethanolamine
Phosphatidylethanolamine N-methyltransferase
Questionnaires
title The associations between phosphatidylethanolamine N-methyltransferase gene, dietary choline intake and anxiety and depression in healthy UK adults
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