Synthesis and Antimicrobial Activity of (3-Formyl-4-hydroxybenzyl)triphenylphosphonium Chloride Acylhydrazones

In this study, four novel quaternary phosphonium acylhydrazones, derivatives of (3-formyl-4-hydroxybenzyl)triphenylphosphonium chloride, have been synthesized and their structures elucidated from IR and NMR spectra, and elemental analysis. All synthesized compounds have been tested for their antimic...

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Veröffentlicht in:	Russian journal of general chemistry 2020-09, Vol.90 (9), p.1716-1720
Hauptverfasser:	Milenkovic, M. R, Zivkovic-Radovanovic, V, Andjelkovic, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Antiinfectives and antibacterials Antimicrobial agents Chemical analysis Chemistry Chemistry and Materials Science Chemistry/Food Science Chlorides Drug resistance in microorganisms Gram-positive bacteria NMR Nuclear magnetic resonance Nuclear magnetic resonance spectroscopy Synthesis
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Beschreibung
Zusammenfassung:	In this study, four novel quaternary phosphonium acylhydrazones, derivatives of (3-formyl-4-hydroxybenzyl)triphenylphosphonium chloride, have been synthesized and their structures elucidated from IR and NMR spectra, and elemental analysis. All synthesized compounds have been tested for their antimicrobial activity, and acylhydrazones have demonstrated selective activity against Gram-positive bacteria strains.
ISSN:	1070-3632 1608-3350
DOI:	10.1134/S1070363220090194