High plasma soluble levels of the immune checkpoint HLA-G molecule among bodybuilders

Introduction Studies report that intense physical activity influences the down-regulation of immune function in athletes as well as the interaction between adipose tissue and the immune system. Aim This study aimed to compare the plasma soluble levels of the immune checkpoint HLA-G (sHLA-G) molecule...

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Veröffentlicht in:	PloS one 2020-09, Vol.15 (9), p.e0238044-e0238044
Hauptverfasser:	Fernandes, Talita M., Puggina, Enrico F., Mendes-Junior, Celso T., de Paula, Milena C., Sonon, Paulin, Donadi, Eduardo A., Fernandes, Ana Paula M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Accuracy Adipose tissue Age Antibodies Antigens Athletes Biology and Life Sciences Body composition Body fat Bodybuilders Bodybuilding Cytotoxicity Exercise Females Health aspects Histocompatibility antigen HLA HLA antigens Immune checkpoint Immune response Immune system Immunology Males Medicine and Health Sciences Muscles Nursing Physical activity Physical education Physical fitness Physical training Physiological aspects Software Statistical analysis Variance analysis
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Zusammenfassung:	Introduction Studies report that intense physical activity influences the down-regulation of immune function in athletes as well as the interaction between adipose tissue and the immune system. Aim This study aimed to compare the plasma soluble levels of the immune checkpoint HLA-G (sHLA-G) molecule with the fat mass and muscle mass index among 77 bodybuilders and 64 controls. Results The comparisons of the percentage of body fat (%BF) revealed that the groups of male and female bodybuilders showed a statistically significant reduction in the percentage of body fat when compared to their control group, (P
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0238044