Importance of complete blood count parameters and neutrophil-to-lymphocyte ratio in central and peripheral vertigo

Aim: The present study investigated the diagnostic value of complete blood count (CBC) parameters, neutrophil-to-lymphocyte (NLR), mean platelet volume-to-platelet (MPV/PLT), and platelet-to-lymphocyte (PLR) ratios in patients with central vertigo (CV) compared to the value in patients with peripheral vertigo (PV). Methods: This retrospective study included 31 patients with CV and 132 patients with PV. CBC parameters and NLR, MPV/PLT, and PLR were statistically analyzed in all patients with vertigo. Results: Statistically significant differences were found between the CV and PV groups for white blood cell (WBC) count 9.55[+ or -]2.33 and 8.24[+ or -]2.34 x [10.sup.6]/[mm.sup.3] (p=0.006), NLR 3.58[+ or - ]2.16 and 2.96[+ or -]2.47 (p=0.014), neutrophil count 6.49[+ or -]2.38 and 5.27[+ or -]2.23 x [10.sup.6]/[mm.sup.3] (p=0.007), and monocyte count 0.68[+ or -]0.24 and 0.55[+ or -]0.21 x [10.sup.6]/[mm.sup.3] (p=0.003). Conclusion: WBC, neutrophil, and monocyte counts and NLR may be useful in the differential diagnosis of CV and PV. Keywords: Central vertigo, complete blood count, neutrophil-lymphocyte ratio, peripheral vertigo