Thermosensitive Nanoparticles Based on Polyethylenimine as Promising Materials for Biomedical Applications
Thermosensitive nanoparticles were synthesized by acylation of branched polyethyleneimine with isobutyroyl chloride and cross-linking by 1,6-hexamethylene diisocyanate. It was found that colloidal aqueous solutions of these particles reversibly lose solubility around physiological temperature. The i...
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| Veröffentlicht in: | Russian journal of general chemistry 2020-07, Vol.90 (7), p.1312-1316 |
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| container_end_page | 1316 |
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| container_issue | 7 |
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| container_title | Russian journal of general chemistry |
| container_volume | 90 |
| creator | Tenkovtsev, A. V. Kurlykin, M. P. Amirova, A. I. Krasova, A. S. Kirila, T. Yu Filippov, A. P. |
| description | Thermosensitive nanoparticles were synthesized by acylation of branched polyethyleneimine with isobutyroyl chloride and cross-linking by 1,6-hexamethylene diisocyanate. It was found that colloidal aqueous solutions of these particles reversibly lose solubility around physiological temperature. The influence of the composition of the nanoparticle on their hydrodynamic parameters, as well as on the phase transition temperatures in aqueous solutions was evaluated. |
| doi_str_mv | 10.1134/S107036322007018X |
| format | Article |
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The influence of the composition of the nanoparticle on their hydrodynamic parameters, as well as on the phase transition temperatures in aqueous solutions was evaluated.</description><identifier>ISSN: 1070-3632</identifier><identifier>EISSN: 1608-3350</identifier><identifier>DOI: 10.1134/S107036322007018X</identifier><language>eng</language><publisher>Moscow: Pleiades Publishing</publisher><subject>Acylation ; Aqueous solutions ; Biomedical materials ; Chemistry ; Chemistry and Materials Science ; Chemistry/Food Science ; Crosslinking ; Drug delivery systems ; Drugs ; Hexamethylene diisocyanate ; Isocyanates ; Nanoparticles ; Phase transitions ; Physiological aspects ; Polyethyleneimine ; Technology application ; Vehicles</subject><ispartof>Russian journal of general chemistry, 2020-07, Vol.90 (7), p.1312-1316</ispartof><rights>Pleiades Publishing, Ltd. 2020</rights><rights>COPYRIGHT 2020 Springer</rights><rights>Pleiades Publishing, Ltd. 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c383t-d703d29e5d54cc53db17513749e57e62456848ade2a01cbafb871a269c71d7d43</citedby><cites>FETCH-LOGICAL-c383t-d703d29e5d54cc53db17513749e57e62456848ade2a01cbafb871a269c71d7d43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1134/S107036322007018X$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1134/S107036322007018X$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids></links><search><creatorcontrib>Tenkovtsev, A. 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| source | Springer Nature - Complete Springer Journals |
| subjects | Acylation Aqueous solutions Biomedical materials Chemistry Chemistry and Materials Science Chemistry/Food Science Crosslinking Drug delivery systems Drugs Hexamethylene diisocyanate Isocyanates Nanoparticles Phase transitions Physiological aspects Polyethyleneimine Technology application Vehicles |
| title | Thermosensitive Nanoparticles Based on Polyethylenimine as Promising Materials for Biomedical Applications |
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