Hepatoprotective Activity of Leucas cephalotes against Paracetamol induced Hepatotoxicity in Rats

The principle causes of carbon tetrachloride is induced hepatic damage in lipid peroxidation and decreased activities of antioxidant enzymes and generation of free radicals. [...]on the 8th day single dose of Paracetamol 2g/kg was given to all group rats except rats in group I. On the 9th day, after 24 hours of Paracetamol administration blood samples were collected by direct cardiac puncture under light ether anesthesia. The drugs like Silymarin and the plant extract decreased increase enzyme levels in tested groups, indicating the protection of liver cell membrane or regeneration of damaged liver cells. Protective effect of pineapple (Ananas cosmosus) peel extract on alcohol-induced oxidative stress in brain tissues of male albino rats.