Al(OTf)3‐Catalyzed Tandem Coupling Reaction between N,N‐Disubstituted Aminomalonitriles and Substituted Arenes: a Synthesis of 1‐Cyano‐bisindolylmethane Analogues

Al(OTf)3‐Catalyzed Tandem Coupling Reaction between N,N‐Disubstituted Aminomalonitriles and Substituted Arenes: a Synthesis of 1‐Cyano‐bisindolylmethane Analogues

A synthesis of 1‐cyano‐bisindolylmethane analogues via an Al(OTf)3‐catalyzed tandem coupling reaction between N,N‐disubstituted aminomalonitriles and substituted arenes has been developed. This method not only provides an alternative synthetic strategy for the synthesis of corresponding functional m...

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Veröffentlicht in:Advanced synthesis & catalysis 2020-07, Vol.362 (14), p.2870-2875
Hauptverfasser: Lei, Lin‐Sheng, Wang, Bo‐Wen, Jin, Da‐Ping, Gao, Zhu‐Peng, Huan‐Liang, Wang, Shao‐Hua, Xu, Xue‐Tao, Zhang, Kun, Zhang, Xiao‐Yun
Format: Artikel
Sprache:eng
Schlagworte:
1-cyano-bisindolylmethane
Aromatic compounds
bisarylmethanes
Chemical synthesis
Coupling
Coupling (molecular)
decyanation
N,N-disubstituted aminomalonitriles
Substitutes
tandem reaction
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Zusammenfassung:A synthesis of 1‐cyano‐bisindolylmethane analogues via an Al(OTf)3‐catalyzed tandem coupling reaction between N,N‐disubstituted aminomalonitriles and substituted arenes has been developed. This method not only provides an alternative synthetic strategy for the synthesis of corresponding functional molecules, but also enriches the volume of bisarylmethanes library to facilitate related functional studies.
ISSN:1615-4150
1615-4169
DOI:10.1002/adsc.202000261