Interoceptive Inception in Insula

The neural mechanisms underlying interoception—the sensation of internal physiological states—remain largely unresolved. In this issue of Neuron, Livneh et al. (2020) demonstrate that the insula bridges different timescales of interoception by tracking and predicting thirst and hunger states. The neural mechanisms underlying interoception—the sensation of internal physiological states—remain largely unresolved. In this issue of Neuron, Livneh et al. (2020) demonstrate that the insula bridges different timescales of interoception by tracking and predicting thirst and hunger states.