Yeast Mycocins: a great potential for application in health

ABSTRACT Mycocins have demonstrated inhibition of fungi, bacteria, parasites and viruses, in addition to being studied as epidemiological markers and in the development of vaccines. They are defined as extracellular proteins or glycoproteins with different activities, the main mechanism of action be...

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Veröffentlicht in:FEMS yeast research 2020-05, Vol.20 (3), p.1
Hauptverfasser: Nascimento, Bruna L, Delabeneta, Mateus F, Rosseto, Lana Rubia B, Junges, Daniele S B, Paris, Ana Paula, Persel, Cristiane, Gandra, Rinaldo F
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Sprache:eng
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Zusammenfassung:ABSTRACT Mycocins have demonstrated inhibition of fungi, bacteria, parasites and viruses, in addition to being studied as epidemiological markers and in the development of vaccines. They are defined as extracellular proteins or glycoproteins with different activities, the main mechanism of action being the inhibition of β-glucan synthesis in the cell wall of sensitive strains. Given the resistance problems created by several microorganisms to agents commonly used in clinical practice, the discovery of new substances with this purpose becomes essential. Mycocins have potential as anti-microbials because they show minimal toxicity and do not present resistance. Mycocins are active against a diverse type of microorganisms.
ISSN:1567-1356
1567-1364
DOI:10.1093/femsyr/foaa016