The association between facility volume and overall survival in patients with Merkel cell carcinoma

The association between facility volume and overall survival in patients with Merkel cell carcinoma

Background Merkel cell carcinoma is an uncommon malignancy often requiring multidisciplinary management. The purpose of this study was to determine whether high‐volume facilities have improved outcomes in patients with Merkel cell carcinoma relative to lower‐volume facilities. Methods A total of 530...

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Veröffentlicht in:Journal of surgical oncology 2020-08, Vol.122 (2), p.254-262
Hauptverfasser: Yoshida, Emi J., Luu, Michael, Freeman, Morganna, Essner, Richard, Gharavi, Nima M., Shiao, Stephen L., Mallen‐St. Clair, Jon, Hamid, Omid, Ho, Allen S., Zumsteg, Zachary S.
Format: Artikel
Sprache:eng
Schlagworte:
Cancer surgery
facility characteristics
high‐volume facilities
Merkel cell carcinoma
Skin cancer
Surgical outcomes
Survival analysis
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Zusammenfassung:Background Merkel cell carcinoma is an uncommon malignancy often requiring multidisciplinary management. The purpose of this study was to determine whether high‐volume facilities have improved outcomes in patients with Merkel cell carcinoma relative to lower‐volume facilities. Methods A total of 5304 patients from the National Cancer Database with stage I‐III Merkel cell carcinoma undergoing surgery were analyzed. High‐volume facilities were the top 1% by case volume. Multivariable Cox regression and propensity score‐matching were performed to account for imbalances between groups. Results Treatment at high‐volume facilities (hazard ratio: 0.74; 95% confidence interval: 0.65‐0.84, P 
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.25931