Synthesis of 2‐(Arylthio)indolenines via Chemoselective Arylation of Thio‐Oxindoles with Arynes

A chemoselective S‐arylation reaction of thio‐oxindoles with arynes is presented. The reaction was performed under mild conditions and provided a straightforward synthesis of 2‐(arylthio)indolenines in good to excellent yields. Besides, this simple operational protocol is not only scalable but also...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Advanced synthesis & catalysis 2020-07, Vol.362 (13), p.2683-2688
Hauptverfasser: Saputra, Adi, Fan, Rong, Yao, Tuanli, Chen, Jian, Tan, Jiajing
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A chemoselective S‐arylation reaction of thio‐oxindoles with arynes is presented. The reaction was performed under mild conditions and provided a straightforward synthesis of 2‐(arylthio)indolenines in good to excellent yields. Besides, this simple operational protocol is not only scalable but also has good functional group compatibilities and substrate scope. Thus, our protocol should allow for the expansion of chemical space via developing new scaffolds of thioimidates that are difficult to synthesize otherwise.
ISSN:1615-4150
1615-4169
DOI:10.1002/adsc.202000308