Is laterality of congenital diaphragmatic hernia a reliable prognostic factor? French national cohort study
Objectives The objective of this study was to assess whether the laterality of congenital diaphragmatic hernia (CDH) was a prognostic factor for neonatal survival. Methods This was a cohort study using the French national database of the Reference Center for Diaphragmatic Hernias. The principal endp...
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Veröffentlicht in: | PRENATAL DIAGNOSIS 2020-07, Vol.40 (8), p.949-957 |
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Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Objectives
The objective of this study was to assess whether the laterality of congenital diaphragmatic hernia (CDH) was a prognostic factor for neonatal survival.
Methods
This was a cohort study using the French national database of the Reference Center for Diaphragmatic Hernias. The principal endpoint was survival after hospitalization in intensive care.
We made a comparative study between right CDH and left CDH by univariate and multivariate analysis. Terminations and stillbirths were excluded from analyses of neonatal outcomes.
Results
A total of 506 CDH were included with 67 (13%) right CDH and 439 left CDH (87%). Rate of survival was 49% for right CDH and 74% for left CDH (P |
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ISSN: | 0197-3851 1097-0223 1097-0223 |
DOI: | 10.1002/pd.5706 |