Is laterality of congenital diaphragmatic hernia a reliable prognostic factor? French national cohort study

Objectives The objective of this study was to assess whether the laterality of congenital diaphragmatic hernia (CDH) was a prognostic factor for neonatal survival. Methods This was a cohort study using the French national database of the Reference Center for Diaphragmatic Hernias. The principal endp...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PRENATAL DIAGNOSIS 2020-07, Vol.40 (8), p.949-957
Hauptverfasser: Pinton, Anne, Boubnova, Julia, Becmeur, François, Kuhn, Pierre, Senat, Marie‐Victoire, Stirnemann, Julien, Capelle, Marianne, Rosenblatt, Jonathan, Massardier, Jérôme, Vaast, Pascal, Le Bouar, Gwenaelle, Desrumaux, Amélie, Connant, Laure, Begue, Laetitia, Parmentier, Benoit, Perrotin, Franck, Diguet, Alain, Benoist, Guillaume, Muszynski, Charles, Scalabre, Aurélien, Winer, Norbert, Michel, Jean‐Luc, Casagrandre‐Magne, Florence, Jouannic, Jean‐Marie, Gallot, Denis, Coste Mazeau, Perrine, Sapin, Emmanuel, Maatouk, Alexis, Saliou, Anne‐Hélène, Sentilhes, Loïc, Biquard, Florence, Mottet, Nicolas, Favre, Romain, Benachi, Alexandra, Sananès, Nicolas
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Objectives The objective of this study was to assess whether the laterality of congenital diaphragmatic hernia (CDH) was a prognostic factor for neonatal survival. Methods This was a cohort study using the French national database of the Reference Center for Diaphragmatic Hernias. The principal endpoint was survival after hospitalization in intensive care. We made a comparative study between right CDH and left CDH by univariate and multivariate analysis. Terminations and stillbirths were excluded from analyses of neonatal outcomes. Results A total of 506 CDH were included with 67 (13%) right CDH and 439 left CDH (87%). Rate of survival was 49% for right CDH and 74% for left CDH (P
ISSN:0197-3851
1097-0223
1097-0223
DOI:10.1002/pd.5706