Vasoactive Intestinal Peptide in Checkpoint Inhibitor–Induced Pneumonitis

Vasoactive Intestinal Peptide in Checkpoint Inhibitor–Induced Pneumonitis

A patient with severe autoimmune pneumonitis from immune checkpoint inhibitor therapy for metastatic melanoma had improved clinical and radiographic clearance of the pneumonitis associated with treatment with inhaled vasoactive intestinal peptide.

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Veröffentlicht in:The New England journal of medicine 2020-06, Vol.382 (26), p.2573-2574
Hauptverfasser: Frye, Björn C, Meiss, Frank, von Bubnoff, Dagmar, Zissel, Gernot, Müller-Quernheim, Joachim
Format: Artikel
Sprache:eng
Schlagworte:
Immune checkpoint inhibitors
Immune clearance
Intestine
Lymphocytes
Melanoma
Metastases
Peptides
Pneumonitis
Sarcoidosis
Vasoactive agents
Vasoactive intestinal peptide
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Zusammenfassung:A patient with severe autoimmune pneumonitis from immune checkpoint inhibitor therapy for metastatic melanoma had improved clinical and radiographic clearance of the pneumonitis associated with treatment with inhaled vasoactive intestinal peptide.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMc2000343