LOCAL TOXICITY OF DRY VEGETABLE EXTRACT FROM THE EPILOBIUM PARVIFLORUM SCHREB TESTED ON EXTRACTED TOOTH SOCKET OF ALBINO WISTAR RAT

Modern bacteriological techniques allow the cultivation and identification of microorganisms involved in the bacterial etiology of endodontic infections; the therapeutical purpose in endodontic infections is to remove these bacteria from the endodontic space by using common antiseptics, such as sodium hypochlorite and chlorhexidine. In modern, unconventional practice, endodontic specialists use natural remedies as an adjunct to classical therapy, all the more so as the antibacterial action of plant extracts comes to meet the phenomenon of antibiotic resistance, a problem that has dominated medical practice in the latter millennium and which seems to persist in an upward trend in the third millennium, as well. Tooth socket healing in rats, 7 days after tooth extraction, demonstrated that in the control group (C) the sockets were filled in a hiqher quantity with a fibrinous blood clot, immature fibrovascular granulation tissue (Fig. 5), rich in blood vessels with sprinkles infiltration of chronic inflammatory cells (Fig.7), large areas of hemorrhage, marked hyperemia, areas of hemorrhagic necrosis (Fig. 9), thinning of the periodontal ligament (Fig. 11). [...]with the control group, the sockets treated with dry herbal extract (H) were filled pore with immature fibrovascular granulation tissue (Fig. 6) rich in blood vessels with sprinkles infiltration of chronic inflammatory cells (Fig. 8), limited areas of hemorrhage, hyperemia of the blood vessels dental (Fig. 10), periodontal ligament without modifications (Fig. 12).