ORAL MANIFESTATIONS OF THE CELIAC DISEASE PART I. A SYSTEMATIC REVIEW OF CASE-CONTROLLED STUDIES
[...]publications on the topic reveal visible reporting discrepancies. [...]the aim of our study was to perform a systematic-review of case-controlled observational studies on CD oral manifestations. Despite the relatively constant prevalence reported for such oral manifestations, publications are c...
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| Veröffentlicht in: | International journal of medical dentistry 2020-04, Vol.24 (2), p.165-173 |
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| container_title | International journal of medical dentistry |
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| creator | Nemţeanu, Roxana Bălan, Gheorghe G Mihalaş, Eugeniu Pleşa, Alina Savin, Carmen |
| description | [...]publications on the topic reveal visible reporting discrepancies. [...]the aim of our study was to perform a systematic-review of case-controlled observational studies on CD oral manifestations. Despite the relatively constant prevalence reported for such oral manifestations, publications are characterized by high publication and outcome bias. [...]oral manifestations are influenced by concurring the oral conditions possibly generated by diet and healthcare disparities. [...]CD should be searched in patients with DEDs and aphthous ulcers or RAS, yet the concurring conditions should be ruled out, and a thorough CD diagnosis algorithm should be implemented. The diagnosis is currently defined by 5 components: symptoms, the presence of HLA-DQ2/ DQ8, celiac antibodies in serum, duodenal histology and response to the gluten-free diet [4,5]. Because CD is a multisystem disorder with protean clinical manifestations, a high index of suspicion is needed to make an appropriate diagnosis. |
| format | Article |
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[...]CD should be searched in patients with DEDs and aphthous ulcers or RAS, yet the concurring conditions should be ruled out, and a thorough CD diagnosis algorithm should be implemented. The diagnosis is currently defined by 5 components: symptoms, the presence of HLA-DQ2/ DQ8, celiac antibodies in serum, duodenal histology and response to the gluten-free diet [4,5]. 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| identifier | ISSN: 2066-6063 |
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| issn | 2066-6063 2392-8018 |
| language | eng |
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| source | EZB-FREE-00999 freely available EZB journals |
| subjects | Bias Celiac disease Defects Dental caries Dental enamel Diagnosis Diet Gluten Histocompatibility antigen HLA Pediatrics Studies Systematic review Ulcers |
| title | ORAL MANIFESTATIONS OF THE CELIAC DISEASE PART I. A SYSTEMATIC REVIEW OF CASE-CONTROLLED STUDIES |
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