Synthesis and Anti-Proliferative Activity of Novel Tricyclic Compounds Derived from 2-Substituted 1,3-Indandione

Synthesis and Anti-Proliferative Activity of Novel Tricyclic Compounds Derived from 2-Substituted 1,3-Indandione

A new series of fused 1,3-indandione derivatives has been synthesized and evaluated for anti-proliferative activity. 2-Alkene-1,3-indandione derivatives have been used as the precursors of a number of tricyclic compounds. The latter have been tested for anti-proliferative activity.

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Veröffentlicht in:Russian journal of general chemistry 2020-04, Vol.90 (4), p.686-696
Hauptverfasser: Abd-Elghaffar, H. S., El-Hashash, M. A., Mohamed, S. F., Ibrahim, A. A., Amr, A. E., Al-Omar, M. A., Nossier, E. S.
Format: Artikel
Sprache:eng
Schlagworte:
Antiproliferatives
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Derivatives
Indandione
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Zusammenfassung:A new series of fused 1,3-indandione derivatives has been synthesized and evaluated for anti-proliferative activity. 2-Alkene-1,3-indandione derivatives have been used as the precursors of a number of tricyclic compounds. The latter have been tested for anti-proliferative activity.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363220040209