Synthesis and Cytotoxicity of Quinazolin-4(3H)-one Based Peptides

A novel series of quinazolin-4(3 H )-one derivatives has been synthesized in high yields using the multicomponent Ugi reaction and characterized by IR, NMR and mass spectral data. The products have been tested for their cytotoxic activity against HeLa cells. Two tested compounds have shown potent ac...

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Veröffentlicht in:	Russian journal of general chemistry 2020-04, Vol.90 (4), p.720-724
Hauptverfasser:	Shankaraiah, P., Bhavani, A. K. D., Kumar, A. Kishore, Ramakrishna, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Chemistry and Materials Science Chemistry/Food Science Doxorubicin NMR Nuclear magnetic resonance Peptides Quinones Reductases Toxicity
Online-Zugang:	Volltext
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